trouble, perplexity

IRRITATION
List of words for the clue trouble, perplexity from the crossword:
DISTRESS ANXIETY SNARL KNOT TANGLE SECRET QUANDARY MYSTERY MUDDINESS MAZE ENIGMA DISARRAY DILEMMA CONFUSION CONFUSEDNESS UHOH LISP HOTWATER
WordClue
ADOtrouble, fuss
ROWtrouble, hardship
WOEtrouble, bewilderment
CAREtrouble, anxiety
EVILcalamity, trouble
FUSStrouble, torment
PAINtrouble, ado
GRIEFtrouble, discomfort
ANXIETYdistress, perplexity
TROUBLEperplexity, pain
DISTRESSanxiety, perplexity
ANNOYANCEinconvenience, trouble
SUFFERINGtrouble, plague
AFFLICTIONtrouble, grief
DISCOMFORTtrouble, inconvenience
IMPEDIMENTembarrassment, trouble
MISFORTUNEtrouble, trial
PERPLEXITYtrouble, pain
UNEASINESStrouble, annoyance
VISITATIONtrouble, affliction
PERPLEXITYtrouble, pain
SUFFERINGtrouble, plague